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Martin Borggrefe Selected Research

Short Qt Syndrome

1/2021Effects of Antiarrhythmic Drugs on hERG Gating in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1.
1/2020Ionic Mechanisms of Disopyramide Prolonging Action Potential Duration in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1.
10/2019Long-term follow-up of implantable cardioverter-defibrillators in Short QT syndrome.
1/2019Drug Testing in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1.
1/2019Modeling Reentry in the Short QT Syndrome With Human-Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets.
1/2019Impact of Antiarrhythmic Drugs on the Outcome of Short QT Syndrome.
1/2018Modeling Short QT Syndrome Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
11/2008Short QT syndrome. Update on a recent entity.
6/2007Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.
5/2007[Short QT syndrome].
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Martin Borggrefe Research Topics

Disease

50Heart Failure
01/2022 - 04/2004
44Ventricular Tachycardia
01/2022 - 01/2004
27Atrial Fibrillation
01/2022 - 10/2002
24Brugada Syndrome
05/2022 - 02/2002
23Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2022 - 08/2002
21Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 01/2009
21Myocardial Infarction
01/2021 - 01/2003
20Sepsis (Septicemia)
06/2018 - 02/2004
17Coronary Artery Disease (Coronary Atherosclerosis)
02/2022 - 10/2007
17Short Qt Syndrome
01/2021 - 12/2003
16Cardiac Arrhythmias (Arrythmia)
01/2021 - 09/2003
16Ventricular Fibrillation
10/2019 - 12/2004
16Inflammation (Inflammations)
01/2017 - 01/2003
15Shock
01/2022 - 10/2002
13Cardiomyopathies (Cardiomyopathy)
01/2022 - 10/2011
12Sudden Death
01/2021 - 03/2004
12Takotsubo Cardiomyopathy
01/2021 - 01/2005
11Pathologic Constriction (Stenosis)
03/2020 - 05/2002
9Syncope (Fainting)
01/2022 - 08/2002
9Cardiogenic Shock
01/2021 - 01/2010
9ST Elevation Myocardial Infarction
01/2018 - 01/2006
8Stroke (Strokes)
12/2021 - 12/2011
8Death (Near-Death Experience)
01/2021 - 10/2018
8Atherosclerosis
01/2021 - 01/2012
8Tachycardia (Tachyarrhythmias)
01/2020 - 01/2004
8Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
01/2020 - 01/2007
8Aortic Valve Stenosis (Aortic Stenosis)
09/2008 - 09/2002
7Heart Diseases (Heart Disease)
12/2021 - 01/2006
6Septic Shock (Toxic Shock Syndrome)
07/2020 - 09/2014
6Heart Arrest (Cardiac Arrest)
01/2020 - 02/2003
6Hemorrhage
05/2019 - 07/2008
6Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2018 - 10/2007
5Pulmonary Embolism
06/2018 - 01/2007
5Fibrosis (Cirrhosis)
01/2017 - 05/2010
4Neoplasms (Cancer)
01/2022 - 01/2018
4Hypertension (High Blood Pressure)
12/2021 - 01/2007
4Chronic Renal Insufficiency
11/2020 - 01/2015
4Infections
01/2020 - 05/2004
4Thrombosis (Thrombus)
01/2018 - 09/2007
4Dyspnea (Shortness of Breath)
01/2015 - 09/2008
4Edema (Dropsy)
01/2015 - 09/2008
4Chest Pain (Chest Pains)
11/2012 - 01/2005
4Acute Coronary Syndrome
08/2006 - 01/2005
3Breast Neoplasms (Breast Cancer)
12/2021 - 04/2009
3Ischemic Stroke
01/2021 - 01/2012
3Cicatrix (Scar)
01/2021 - 09/2009
3Right Ventricular Dysfunction
01/2021 - 12/2014
3Hyperkalemia
03/2020 - 02/2005

Drug/Important Bio-Agent (IBA)

25Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2004
17omega-Chloroacetophenone (Mace)IBA
01/2022 - 01/2009
14pro-brain natriuretic peptide (1-76)IBA
12/2018 - 01/2004
12GadoliniumIBA
01/2021 - 01/2005
10Ion Channels (Ion Channel)IBA
01/2022 - 07/2005
9Anti-Arrhythmia AgentsIBA
01/2021 - 04/2004
8Pharmaceutical PreparationsIBA
01/2019 - 04/2004
8Troponin IIBA
01/2019 - 01/2005
8Protein CIBA
10/2018 - 01/2003
7Sodium Channels (Sodium Channel)IBA
05/2022 - 09/2002
7Proteins (Proteins, Gene)FDA Link
01/2020 - 11/2005
7Interleukin-6 (Interleukin 6)IBA
02/2018 - 01/2006
7CalciumIBA
01/2018 - 09/2002
7Matrix Metalloproteinases (MMPs)IBA
01/2009 - 01/2003
6Ajmaline (Wolfina)FDA Link
01/2019 - 04/2002
6Natriuretic PeptidesIBA
01/2017 - 07/2005
6Brain Natriuretic Peptide (Natrecor)FDA Link
01/2016 - 07/2005
5Potassium Channels (Potassium Channel)IBA
01/2022 - 10/2005
5TroponinIBA
01/2021 - 11/2012
5Phenobarbital (Luminal)FDA Link
03/2020 - 01/2010
5Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
05/2019 - 04/2006
5CytokinesIBA
09/2012 - 01/2004
5CD40 Ligand (CD40L)IBA
01/2012 - 03/2006
5Atrial Natriuretic Factor (ANF)IBA
04/2011 - 01/2004
5drotrecogin alfa activated (Xigris)FDA Link
01/2011 - 07/2005
5LipopolysaccharidesIBA
01/2008 - 05/2004
4sacubitril and valsartan sodium hydrate drug combinationIBA
01/2021 - 10/2019
4PotassiumIBA
10/2020 - 06/2007
4CatecholaminesIBA
01/2019 - 01/2017
4Sodium Channel BlockersIBA
01/2018 - 02/2005
4Flecainide (Tambocor)FDA LinkGeneric
06/2017 - 04/2004
4C-Reactive ProteinIBA
03/2016 - 11/2005
4AdrenomedullinIBA
01/2016 - 01/2008
4EnzymesIBA
08/2012 - 01/2005
4fibrin fragment D (D-dimer)IBA
03/2009 - 07/2003
4Quinidine (Chinidin)FDA LinkGeneric
06/2007 - 01/2005
4azimilideIBA
09/2006 - 12/2004
3Antidepressive Agents (Antidepressants)IBA
11/2020 - 02/2005
3AnticoagulantsIBA
11/2020 - 09/2006
3ThrombinFDA Link
07/2020 - 07/2003

Therapy/Procedure

81Therapeutics
09/2022 - 09/2003
50Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
01/2022 - 12/2003
16Defibrillators (Defibrillator)
01/2021 - 02/2003
14Patient Readmission
01/2022 - 08/2017
12Percutaneous Coronary Intervention
01/2020 - 01/2006
11Stents
08/2016 - 05/2002
8Electric Countershock (Cardioversion)
02/2022 - 10/2002
7Cardiopulmonary Resuscitation (CPR)
01/2021 - 01/2010
7Critical Care (Surgical Intensive Care)
06/2018 - 02/2004
6Catheter Ablation
01/2021 - 08/2002
6Cardiac Resynchronization Therapy
03/2020 - 12/2005
4Drug Therapy (Chemotherapy)
01/2022 - 04/2006